What sequence should be followed for a suspected transfusion reaction?

• A. Stop transfusion; monitor; call provider; restart transfusion.
• B. Stop transfusion; Maintain IV NS; Notify provider/blood bank; Return blood bag.
• C. Continue transfusion with slower rate.
• D. Administer antihistamines.

Answer: (B)

When a transfusion reaction is suspected, the priority is to protect the patient and quickly gather information. Stop the transfusion immediately to prevent further exposure to the reacting product. Keep the IV line open with normal saline to maintain circulation and have access for medications if needed. Notify the provider and the blood bank right away so they can assess the patient, initiate appropriate treatment, and determine the next steps for the transfusion product. Return the blood bag and tubing to the blood bank for investigation and tracing of the product. This sequence ensures immediate safety, supports rapid clinical management, and preserves vital information for investigation.