What is the priority action for a neutropenic patient with a temperature of 100.6°F?

• A. Notify provider immediately
• B. Administer acetaminophen and observe
• C. Increase oral fluids
• D. Document and continue monitoring

Answer: (B)

When a patient is neutropenic, any fever is a red flag. The main idea is that fever in this context can signal a serious infection that the body can’t mount a strong fight against, so rapid action is essential.

The priority action is to notify the provider immediately so orders for prompt evaluation and empiric antibiotic therapy can be started without delay. Time matters because delays in antibiotic treatment for neutropenic fever can lead to rapid deterioration. While giving acetaminophen may help reduce fever and make the patient more comfortable, it does not treat the underlying infection and can mask symptoms, delaying the urgent workup and treatment that are needed. After notifying the provider, expect steps like obtaining cultures (blood, urine, and any other sites as indicated), initiating neutropenic precautions, and starting broad-spectrum IV antibiotics as soon as possible, with ongoing monitoring and supportive care.