What action should be taken first if a transfusion reaction is suspected?

• A. Notify the provider.
• B. Stop the transfusion.
• C. Administer IV fluids.
• D. Return the blood product.

Answer: (B)

Stopping the transfusion immediately is the priority when a transfusion reaction is suspected. Halting the infusion prevents further exposure to the donor blood and limits ongoing injury, which is the fastest way to protect the patient. After stopping, keep the patient on IV access with normal saline, monitor vital signs, and notify the provider so treatment can begin. The blood product should be kept for investigation and returned to the blood bank with tubing and labeling. Subsequent steps, such as giving IV fluids or other therapies, are carried out as ordered after the initial action has been taken.